Final Project Essay

938 words - 4 pages

Hemophilia is bleeding disorder that slows the clotting process of blood. Hemophilia is be a big problem because it can be lethal if a person affected with the disease were to get into an accident because their blood would not be able to clot, causing them to bleed out and die. Therefore something must be done in order to prevent this incident from occurring in the future. Currently there is no cure to hemophilia, only possible treatments for the symptoms. The purpose of this model is to find the best way to combat the effects of this disease, either by increasing funding to help find the cure, stopping the reproduction of people with hemophilia, or by simply letting nature take its course. ...view middle of the document...

However, this gene is sex-linked, meaning it occurs on the 23rd chromosome of DNA, which just happens to determine the sex of the host. If the host is a female, they will carry two copies of the X gene, while if they are male they will carry one copy of the X chromosome and one copy of the Y chromosome. Therefore, any gene carried on an X chromosome will always be observed when the host is a male because they do not have a second copy that may be different as with any other chromosome. Therefore, when the father is affected, all of his female children will have the disorder, while if the mother is affected, all of her male children will have this disorder. This is displayed in the Punnet Squares shown below.
This project includes two models, the first to determine if the genetic disorder is worth studying by looking at a specific line in the pedigree of the family by determining how many people could be affected by the disorder over a period of 40 generations. This was done by creating a Monte Carlo type model, in which the type of chromosome each of the initial two parents are given and the offspring is generated with a 50/50 chance of getting a chromosome from parent 1 or parent 2 for each copy. This offspring is then paired with the offspring of randomly generated parents since it can be assumed the person who you will have children with in the future is completely random. These two offsprings are then used to generate an offspring of their own, which is paired with another offspring from two other randomly generated parents. This process is repeated over a period of 40...

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